Ontology highlight
ABSTRACT:
SUBMITTER: Summers JA
PROVIDER: S-EPMC5009271 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Summers Jody A JA Harper Angelica R AR Feasley Christa L CL Van-Der-Wel Hanke H Byrum Jennifer N JN Hermann Marcela M West Christopher M CM
The Journal of biological chemistry 20160711 36
All-trans-retinoic acid may be an important molecular signal in the postnatal control of eye size. The goal of this study was to identify retinoic acid-binding proteins secreted by the choroid and sclera during visually guided ocular growth. Following photoaffinity labeling with all-trans-[11,12-(3)H]retinoic acid, the most abundant labeled protein detected in the conditioned medium of choroid or sclera had an apparent Mr of 27,000 Da. Following purification and mass spectrometry, the Mr 27,000 ...[more]