Ontology highlight
ABSTRACT:
SUBMITTER: Rempe RG
PROVIDER: S-EPMC5012524 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Rempe Ralf G RG Hartz Anika M S AMS Bauer Björn B
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20160620 9
Matrix metalloproteinases are versatile endopeptidases with many different functions in the body in health and disease. In the brain, matrix metalloproteinases are critical for tissue formation, neuronal network remodeling, and blood-brain barrier integrity. Many reviews have been published on matrix metalloproteinases before, most of which focus on the two best studied matrix metalloproteinases, the gelatinases MMP-2 and MMP-9, and their role in one or two diseases. In this review, we provide a ...[more]