Ontology highlight
ABSTRACT:
SUBMITTER: Romo-Bucheli D
PROVIDER: S-EPMC5013328 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Romo-Bucheli David D Janowczyk Andrew A Gilmore Hannah H Romero Eduardo E Madabhushi Anant A
Scientific reports 20160907
Early stage estrogen receptor positive (ER+) breast cancer (BCa) treatment is based on the presumed aggressiveness and likelihood of cancer recurrence. Oncotype DX (ODX) and other gene expression tests have allowed for distinguishing the more aggressive ER+ BCa requiring adjuvant chemotherapy from the less aggressive cancers benefiting from hormonal therapy alone. However these tests are expensive, tissue destructive and require specialized facilities. Interestingly BCa grade has been shown to b ...[more]