Ontology highlight
ABSTRACT:
SUBMITTER: Klose AD
PROVIDER: S-EPMC6189049 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Klose Alexander D AD Paragas Neal N
Nature communications 20181015 1
We developed a computer-aided analysis tool for quantitatively determining bioluminescent reporter distributions inside small animals. The core innovations are a body-fitting animal shuttle and a statistical mouse atlas, both of which are spatially aligned and scaled according to the animal's weight, and hence provide data congruency across animals of varying size and pose. In conjunction with a multispectral bioluminescence tomography technique capitalizing on the spatial framework of the shutt ...[more]