Ontology highlight
ABSTRACT:
SUBMITTER: Pais-Vieira M
PROVIDER: S-EPMC5015048 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Pais-Vieira Miguel M Yadav Amol P AP Moreira Derek D Guggenmos David D Santos Amílcar A Lebedev Mikhail M Nicolelis Miguel A L MAL
Scientific reports 20160908
Although electrical neurostimulation has been proposed as an alternative treatment for drug-resistant cases of epilepsy, current procedures such as deep brain stimulation, vagus, and trigeminal nerve stimulation are effective only in a fraction of the patients. Here we demonstrate a closed loop brain-machine interface that delivers electrical stimulation to the dorsal column (DCS) of the spinal cord to suppress epileptic seizures. Rats were implanted with cortical recording microelectrodes and s ...[more]