Ontology highlight
ABSTRACT:
SUBMITTER: Pitmon E
PROVIDER: S-EPMC5021212 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Pitmon E E Stephens G G Parkhurst S J SJ Wolf F W FW Kehne G G Taylor M M Lebestky T T
Genes, brain, and behavior 20160129 3
Drosophila groom away debris and pathogens from the body using their legs in a stereotyped sequence of innate motor behaviors. Here, we investigated one aspect of the grooming repertoire by characterizing the D1 family dopamine receptor, DopR. Removal of DopR results in decreased hind leg grooming, as substantiated by quantitation of dye remaining on mutant and RNAi animals vs. controls and direct scoring of behavioral events. These data are also supported by pharmacological results that D1 rece ...[more]