Ontology highlight
ABSTRACT:
SUBMITTER: Qian F
PROVIDER: S-EPMC5021583 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Qian Frank F Feng Ye Y Zheng Yonglan Y Ogundiran Temidayo O TO Ojengbede Oladosu O Zheng Wei W Blot William W Ambrosone Christine B CB John Esther M EM Bernstein Leslie L Hu Jennifer J JJ Ziegler Regina G RG Nyante Sarah S Bandera Elisa V EV Ingles Sue A SA Press Michael F MF Nathanson Katherine L KL Hennis Anselm A Nemesure Barbara B Ambs Stefan S Kolonel Laurence N LN Olopade Olufunmilayo I OI Haiman Christopher A CA Huo Dezheng D
Human genetics 20160705 10
MicroRNAs (miRNA) regulate breast biology by binding to specific RNA sequences, leading to RNA degradation and inhibition of translation of their target genes. While germline genetic variations may disrupt some of these interactions between miRNAs and their targets, studies assessing the relationship between genetic variations in the miRNA network and breast cancer risk are still limited, particularly among women of African ancestry. We systematically put together a list of 822 and 10,468 geneti ...[more]