Ontology highlight
ABSTRACT:
SUBMITTER: Hillmann F
PROVIDER: S-EPMC5022050 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Hillmann Falk F Bagramyan Karine K Straßburger Maria M Heinekamp Thorsten T Hong Teresa B TB Bzymek Krzysztof P KP Williams John C JC Brakhage Axel A AA Kalkum Markus M
Scientific reports 20160914
Invasive aspergillosis and other fungal infections occur in immunocompromised individuals, including patients who received blood-building stem cell transplants, patients with chronic granulomatous disease (CGD), and others. Production of reactive oxygen species (ROS) by immune cells, which incidentally is defective in CGD patients, is considered to be a fundamental process in inflammation and antifungal immune response. Here we show that the peroxiredoxin Asp f3 of Aspergillus fumigatus inactiva ...[more]