Ontology highlight
ABSTRACT:
SUBMITTER: Baars A
PROVIDER: S-EPMC5023267 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Baars Annemarie A Oosting Annemarie A Knol Jan J Garssen Johan J van Bergenhenegouwen Jeroen J
Microorganisms 20151010 4
The gut microbiota plays a crucial role in regulating many physiological systems of the host, including the metabolic and immune system. Disturbances in microbiota composition are increasingly correlated with disease; however, the underlying mechanisms are not well understood. Recent evidence suggests that changes in microbiota composition directly affect the metabolism of bile salts. Next to their role in digestion of dietary fats, bile salts function as signaling molecules for bile salt recept ...[more]