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Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes.

ABSTRACT: Combining the numerous advantages of using light as a stimulus, simple free radical random copolymerization, and the easy, all-aqueous preparation of polyelectrolyte complexes (PECs), we prepared photolabile PEC nanoparticles and demonstrated their rapid degradation under UV light. As a proof of concept demonstration, the dye Nile Red was encapsulated in the PECs and successfully released into the surrounding solution as the polyelectrolyte nanocomplex carriers dissolved upon light irradiation.

SUBMITTER: Hu X

PROVIDER: S-EPMC5025818 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature

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Triggered Release of Encapsulated Cargo from Photoresponsive Polyelectrolyte Nanocomplexes.

Hu Xiaoran X Feeney Matthew J MJ McIntosh Ethan E Mullahoo James J Jia Feng F Xu Qiaobing Q Thomas Samuel W SW

ACS applied materials & interfaces 20160830 36

Combining the numerous advantages of using light as a stimulus, simple free radical random copolymerization, and the easy, all-aqueous preparation of polyelectrolyte complexes (PECs), we prepared photolabile PEC nanoparticles and demonstrated their rapid degradation under UV light. As a proof of concept demonstration, the dye Nile Red was encapsulated in the PECs and successfully released into the surrounding solution as the polyelectrolyte nanocomplex carriers dissolved upon light irradiation. ...[more]

PMID: 27526052

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