Ontology highlight
ABSTRACT:
SUBMITTER: Kumar A
PROVIDER: S-EPMC5025897 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Kumar Anita A Casulo Carla C Yahalom Joachim J Schöder Heiko H Barr Paul M PM Caron Philip P Chiu April A Constine Louis S LS Drullinsky Pamela P Friedberg Jonathan W JW Gerecitano John F JF Hamilton Audrey A Hamlin Paul A PA Horwitz Steven M SM Jacob Alexandra G AG Matasar Matthew J MJ McArthur Gianna N GN McCall Susan J SJ Moskowitz Alison J AJ Noy Ariela A Palomba Maria L ML Portlock Carol S CS Straus David J DJ VanderEls Nicholas N Verwys Stephanie L SL Yang Joanna J Younes Anas A Zelenetz Andrew D AD Zhang Zhigang Z Moskowitz Craig H CH
Blood 20160725 11
This multicenter pilot study assessed the safety and efficacy of brentuximab vedotin (BV) and AVD (adriamycin, vinblastine, and dacarbazine) followed by 30 Gy involved site radiation therapy (ISRT). Patients with newly diagnosed, early stage classical Hodgkin lymphoma (HL) with unfavorable-risk features were treated with 4 cycles of BV and AVD. Patients who achieved a negative positron emission tomography (PET) scan (Deauville score of 1-3) received 30 Gy ISRT. Thirty patients received treatment ...[more]