Ontology highlight
ABSTRACT:
SUBMITTER: Corcoran EB
PROVIDER: S-EPMC5027643 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20160623 6296
Over the past two decades, there have been major developments in transition metal-catalyzed aminations of aryl halides to form anilines, a common structure found in drug agents, natural product isolates, and fine chemicals. Many of these approaches have enabled highly efficient and selective coupling through the design of specialized ligands, which facilitate reductive elimination from a destabilized metal center. We postulated that a general and complementary method for carbon-nitrogen bond for ...[more]