Ontology highlight
ABSTRACT:
SUBMITTER: Kawamata Y
PROVIDER: S-EPMC6996791 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20190402 15
C-N cross-coupling is one of the most valuable and widespread transformations in organic synthesis. Largely dominated by Pd- and Cu-based catalytic systems, it has proven to be a staple transformation for those in both academia and industry. The current study presents the development and mechanistic understanding of an electrochemically driven, Ni-catalyzed method for achieving this reaction of high strategic importance. Through a series of electrochemical, computational, kinetic, and empirical ...[more]