Ontology highlight
ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC5029672 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Chen Xiaohua X Liu Binjian B Yang Rui R Guo Yong Y Li Feng F Wang Lin L Hu Hanyang H
Oncotarget 20160401 17
Accumulating evidence highlights the role of long non-coding RNAs (lncRNAs) in tumors. However, the genome-wide expression and roles of lncRNAs in colorectal cancer (CRC) remain unknown. Here, we systematically examined the global gene expressions in primary and synchronous liver metastases CRC tissue, in which thousands of aberrantly expressed lncRNAs were characterized. Co-expression analysis revealed that some lncRNAs correlated to their neighboring mRNAs in expression levels, whereas others ...[more]