Ontology highlight
ABSTRACT:
SUBMITTER: Luo J
PROVIDER: S-EPMC5400657 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Luo Jian J Qu Jian J Wu Dong-Kai DK Lu Zhi-Li ZL Sun Yue-Sheng YS Qu Qiang Q
Oncotarget 20170301 13
Colorectal cancer (CRC) is a common gastrointestinal cancer, with a high incidence and high mortality. Long non-coding RNAs (lncRNAs) are involved in the development, invasion and metastasis, early diagnosis, prognosis, the chemoresistance and radioresistance of CRC through interference with mRNA activity, directly combining with proteins to regulate their activity or alter their localization, influencing downstream gene expression by inhibiting RNA polymerase and regulating gene expression as c ...[more]