Ontology highlight
ABSTRACT:
SUBMITTER: D'Esposito V
PROVIDER: S-EPMC5029717 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
D'Esposito Vittoria V Liguoro Domenico D Ambrosio Maria Rosaria MR Collina Francesca F Cantile Monica M Spinelli Rosa R Raciti Gregory Alexander GA Miele Claudia C Valentino Rossella R Campiglia Pietro P De Laurentiis Michelino M Di Bonito Maurizio M Botti Gerardo G Franco Renato R Beguinot Francesco F Formisano Pietro P
Oncotarget 20160401 17
Growing evidence indicates that adiposity is associated with raised cancer incidence, morbidity and mortality. In a subset of tumors, cancer cell growth and/or metastasis predominantly occur in adipocyte-rich microenvironment. Indeed, adipocytes represent the most abundant cell types surrounding breast cancer cells. We have studied the mechanisms by which peritumoral human adipose tissue contributes to Triple Negative Breast Cancer (TNBC) cell invasiveness and dissemination.Co-culture with human ...[more]