Ontology highlight
ABSTRACT:
SUBMITTER: Kakimoto Y
PROVIDER: S-EPMC5029930 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Kakimoto Yu Y Tanaka Masayuki M Kamiguchi Hiroshi H Ochiai Eriko E Osawa Motoki M
PloS one 20160920 9
MicroRNAs (miRNAs) are small non-coding RNAs responsible for fine-tuning of gene expression at post-transcriptional level. The alterations in miRNA expression levels profoundly affect human health and often lead to the development of severe diseases. Currently, high throughput analyses, such as microarray and deep sequencing, are performed in order to identify miRNA biomarkers, using archival patient tissue samples. MiRNAs are more robust than longer RNAs, and resistant to extreme temperatures, ...[more]