Ontology highlight
ABSTRACT:
SUBMITTER: Su Z
PROVIDER: S-EPMC5034232 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Su Zheng Z Zhang Junjie J Kumar Chanchal C Molony Cliona C Lu Hongchao H Chen Ronghua R Stone David J DJ Ling Fei F Liu Xiao X
Scientific reports 20160923
Nonhuman primates (NHP) are important biomedical animal models for the study of human disease. Of these, the most widely used models in biomedical research currently are from the genus Macaca. However, evolutionary genetic divergence between human and NHP species makes human-based probes inefficient for the capture of genomic regions of NHP for sequencing and study. Here we introduce a new method to resequence the exome of NHP species by a designed capture approach specifically targeted to the N ...[more]