Ontology highlight
ABSTRACT:
SUBMITTER: Rosenstock J
PROVIDER: S-EPMC5034797 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Rosenstock J J Jelaska A A Zeller C C Kim G G Broedl U C UC Woerle H J HJ
Diabetes, obesity & metabolism 20150714 10
<h4>Aims</h4>To investigate the efficacy and tolerability of empagliflozin added to basal insulin-treated type 2 diabetes.<h4>Methods</h4>Patients inadequately controlled [glycated haemoglobin (HbA1c) >7 to ≤10% (>53 to ≤86 mmol/mol)] on basal insulin (glargine, detemir, NPH) were randomized to empagliflozin 10 mg (n = 169), empagliflozin 25 mg (n = 155) or placebo (n = 170) for 78 weeks. The baseline characteristics were balanced among the groups [mean HbA1c 8.2% (67 mmol/mol), BMI 32.2 kg/m(2) ...[more]