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Data of methylome and transcriptome derived from human dilated cardiomyopathy.

ABSTRACT: Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the right ventricle (RV, a proxy for normal hearts). The data in this DiB are for supporting our report entitled "Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy" (Bong-Seok Jo, In-Uk Koh, Jae-Bum Bae, Ho-Yeong Yu, Eun-Seok Jeon, Hae-Young Lee, Jae-Joong Kim, Murim Choi, Sun Shim Choi, 2016) [1].

SUBMITTER: Jo BS 

PROVIDER: S-EPMC5035344 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

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Data of methylome and transcriptome derived from human dilated cardiomyopathy.

Jo Bong-Seok BS   Koh In-Uk IU   Bae Jae-Bum JB   Yu Ho-Yeong HY   Jeon Eun-Seok ES   Lee Hae-Young HY   Kim Jae-Joong JJ   Choi Murim M   Choi Sun Shim SS  

Data in brief 20160914

Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the right ventricle (RV, a proxy for normal hearts). The data in this DiB are for supporting our report entitled "Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left  ...[more]

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