Ontology highlight
ABSTRACT:
SUBMITTER: Nebesio TD
PROVIDER: S-EPMC5036261 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Nebesio Todd D TD Renbarger Jamie L JL Nabhan Zeina M ZM Ross Sydney E SE Slaven James E JE Li Lang L Walvoord Emily C EC Eugster Erica A EA
International journal of pediatric endocrinology 20160926
<h4>Background</h4>Little is known about the comparative effects of different glucocorticoids on the adrenal and growth hormone (GH) axes in children with congenital adrenal hyperplasia (CAH). We sought to compare the effects of hydrocortisone (HC), prednisone (PDN), and dexamethasone (DEX) in children with classic CAH and to investigate a potential role of pharmacogenetics.<h4>Methods</h4>Subjects were randomly assigned to three sequential 6-week courses of HC, PDN, and DEX, each followed by ev ...[more]