Ontology highlight
ABSTRACT:
SUBMITTER: Cavazza T
PROVIDER: S-EPMC5042580 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Cavazza Tommaso T Malgaretti Paolo P Vernos Isabelle I
Molecular biology of the cell 20160803 19
Centrosome maturation is the process by which the duplicated centrosomes recruit pericentriolar components and increase their microtubule nucleation activity before mitosis. The role of this process in cells entering mitosis has been mostly related to the separation of the duplicated centrosomes and thereby to the assembly of a bipolar spindle. However, spindles can form without centrosomes. In fact, all cells, whether they have centrosomes or not, rely on chromatin-driven microtubule assembly t ...[more]