An iron-oxygen intermediate formed during the catalytic cycle of cysteine dioxygenase.
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ABSTRACT:
SUBMITTER: Tchesnokov EP
PROVIDER: S-EPMC5043143 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Publications
An iron-oxygen intermediate formed during the catalytic cycle of cysteine dioxygenase.
Tchesnokov E P EP Faponle A S AS Davies C G CG Quesne M G MG Turner R R Fellner M M Souness R J RJ Wilbanks S M SM de Visser S P SP Jameson G N L GN
Chemical communications (Cambridge, England) 20160701 57
Cysteine dioxygenase is a key enzyme in the breakdown of cysteine, but its mechanism remains controversial. A combination of spectroscopic and computational studies provides the first evidence of a short-lived intermediate in the catalytic cycle. The intermediate decays within 20 ms and has absorption maxima at 500 and 640 nm. ...[more]
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