Ontology highlight
ABSTRACT:
SUBMITTER: Godsell J
PROVIDER: S-EPMC5052569 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Godsell Jack J Rudloff Ina I Kandane-Rathnayake Rangi R Hoi Alberta A Nold Marcel F MF Morand Eric F EF Harris James J
Scientific reports 20161006
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the development of autoantibodies to nuclear antigens and inflammatory responses mediated by multiple cytokines. Although previous studies have determined clinical associations between SLE and the anti-inflammatory cytokines IL-10 and IL-37, their role in the disease, or their potential as biomarkers, remains unclear. We examined serum levels of IL-10 and IL-37 in a large cohort of SLE patients, with detailed lo ...[more]