Ontology highlight
ABSTRACT:
SUBMITTER: Park S
PROVIDER: S-EPMC5052597 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Scientific reports 20161006
While altered TP53 is the most frequent mutation in gastric cancer (GC), its association with molecular or clinical phenotypes (e.g., overall survival, disease-free survival) remains little known. To that end, we can use genome-wide approaches to identify altered genes significantly related to mutated TP53. Here, we identified significant differences in clinical outcomes, as well as in molecular phenotypes, across specific GC tumor subpopulations, when combining TP53 with other signaling network ...[more]