Ontology highlight
ABSTRACT:
SUBMITTER: Evans JC
PROVIDER: S-EPMC5056232 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
British journal of pharmacology 20160923 21
Prostate specific membrane antigen (PSMA) otherwise known as glutamate carboxypeptidase II (GCPII) is a membrane bound protein that is highly expressed in prostate cancer and in the neovasculature of a wide variety of tumours including glioblastomas, breast and bladder cancers. This protein is also involved in a variety of neurological diseases including schizophrenia and ALS. In recent years, there has been a surge in the development of both diagnostics and therapeutics that take advantage of t ...[more]