Ontology highlight
ABSTRACT:
SUBMITTER: Jimenez-Jimenez FJ
PROVIDER: S-EPMC5059002 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Jiménez-Jiménez Félix Javier FJ García-Martín Elena E Alonso-Navarro Hortensia H Martínez Carmen C Zurdo Martín M Turpín-Fenoll Laura L Millán-Pascual Jorge J Adeva-Bartolomé Teresa T Cubo Esther E Navacerrada Francisco F Rojo-Sebastián Ana A Rubio Lluisa L Ortega-Cubero Sara S Pastor Pau P Calleja Marisol M Plaza-Nieto José Francisco JF Pilo-De-La-Fuente Belén B Arroyo-Solera Margarita M García-Albea Esteban E Agúndez José A G JAG
Medicine 20151101 47
Several recent works suggest a possible role of vitamin D deficiency in the etiology or restless legs syndrome (RLS). We analyzed the possible relationship of 2 common single nucleotide polymorphisms (SNPs) in the vitamin D3 receptor (VDR) gene with the risk for RLS.We studied the genotype and allelic variant frequencies of VDR rs2228570 and VDR rs731236 SNPs in 205 RLS patients and 445 healthy controls using a TaqMan essay.The frequencies of the rs731236AA genotype and the allelic variant rs731 ...[more]