Ontology highlight
ABSTRACT:
SUBMITTER: Pervjakova N
PROVIDER: S-EPMC5066126 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Pervjakova Natalia N Kasela Silva S Morris Andrew P AP Kals Mart M Metspalu Andres A Lindgren Cecilia M CM Salumets Andres A Mägi Reedik R
Epigenomics 20160323 6
Genomic imprinting is an epigenetic feature characterized by parent-specific monoallelic gene expression. The aim of this study was to compare the DNA methylation status of imprinted genes and imprinting control regions (ICRs), harboring differentially methylated regions (DMRs) in a comprehensive panel of 18 somatic tissues. The germline DMRs analyzed were divided into ubiquitously imprinted and placenta-specific DMRs, which show identical and different methylation imprints in adult somatic and ...[more]