Eukaryotic transcription initiation machinery visualized at molecular level.
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ABSTRACT:
SUBMITTER: Han Y
PROVIDER: S-EPMC5066506 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Eukaryotic transcription initiation machinery visualized at molecular level.
Transcription 20161001 5
The structures of RNA Polymerase (Pol) II pre-initiation complexes (PIC) have recently been determined at near-atomic resolution, elucidating unprecedented mechanistic details of promoter opening during transcription initiation. The key structural features of promoter opening are summarized here. Structural knowledge of Pol I and III PIC is also briefly discussed. ...[more]
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