Ontology highlight
ABSTRACT:
SUBMITTER: Chaigneau E
PROVIDER: S-EPMC5067533 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Frontiers in cellular neuroscience 20161018
Optogenetics provides a unique approach to remotely manipulate brain activity with light. Reaching the degree of spatiotemporal control necessary to dissect the role of individual cells in neuronal networks, some of which reside deep in the brain, requires joint progress in opsin engineering and light sculpting methods. Here we investigate for the first time two-photon stimulation of the red-shifted opsin ReaChR. We use two-photon (2P) holographic illumination to control the activation of indivi ...[more]