Ontology highlight
ABSTRACT:
SUBMITTER: Kim SH
PROVIDER: S-EPMC5069390 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Kim Sung-Ho SH Yoo Jung-Hwa JH Lee Woo Je WJ Park Cheol-Young CY
Diabetes & metabolism journal 20160912 5
Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral antidiabetic agent for the treatment of type 2 diabetes mellitus. They increase endogenous levels of incretin hormones, which stimulate glucose-dependent insulin secretion, decrease glucagon secretion, and contribute to reducing postprandial hyperglycemia. Although DPP-4 inhibitors have similar benefits, they can be differentiated in terms of their chemical structure, pharmacology, efficacy and safety profiles, and clinical consid ...[more]