Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez-Vida A
PROVIDER: S-EPMC5070260 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Rodriguez-Vida Alejo A Strijbos Michiel M Hutson Thomas T
ESMO open 20160525 3
In the past decade, several agents targeting angiogenesis and signal transduction pathways have replaced the use of cytokines as standard of care treatment for metastatic renal cell carcinoma (RCC) after showing improved clinical benefit and survival. Currently, several novel immunotherapy agents targeting the programmed cell death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) pathways are being tested in metastatic RCC and are bound to revolutionise the management of this di ...[more]