Ontology highlight
ABSTRACT:
SUBMITTER: Savneby A
PROVIDER: S-EPMC5070843 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
PloS one 20161019 10
The transcriptomes of cells infected with lytic and non-lytic variants of coxsackievirus B2 Ohio-1 (CVB2O) were analyzed using next generation sequencing. This approach was selected with the purpose of elucidating the effects of lytic and non-lytic viruses on host cell transcription. Total RNA was extracted from infected cells and sequenced. The resulting reads were subsequently mapped against the human and CVB2O genomes. The amount of intracellular RNA was measured, indicating lower proportions ...[more]