Ontology highlight
ABSTRACT:
SUBMITTER: Tian T
PROVIDER: S-EPMC5078771 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Tian Tian T Guo Linying L Xu Jing J Zhang Shun S Shi Jingjing J Liu Chengxia C Qin Yuanyuan Y Zhu Wenzhen W
Scientific reports 20161025
Peripheral nerve damage does not fully explain the pathogenesis of trigeminal neuralgia (TN). Central nervous system changes can follow trigeminal nerve dysfunction. We hypothesized that brain white matter and functional connectivity changes in TN patients were involved in pain perception, modulation, the cognitive-affective system, and motor function; moreover, changes in functional reorganization were correlated with white matter alterations. Twenty left TN patients and twenty-two healthy cont ...[more]