NUAK1 (ARK5) Is Associated with Poor Prognosis in Ovarian Cancer.
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ABSTRACT:
SUBMITTER: Phippen NT
PROVIDER: S-EPMC5081368 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
NUAK1 (ARK5) Is Associated with Poor Prognosis in Ovarian Cancer.
Phippen Neil T NT Bateman Nicholas W NW Wang Guisong G Conrads Kelly A KA Ao Wei W Teng Pang-Ning PN Litzi Tracy A TA Oliver Julie J Maxwell G Larry GL Hamilton Chad A CA Darcy Kathleen M KM Conrads Thomas P TP
Frontiers in oncology 20161027
<h4>Background and objective</h4>Nua kinase 1 (NUAK1) was identified in multigene signatures of survival and suboptimal debulking in high-grade serous ovarian cancer (HGSOC). This study investigates the individual clinical and biologic contributions of NUAK1 in HGSOC patients and cell lines.<h4>Methods</h4>Public transcript expression, clinical, and outcome data were used to interrogate the relationship between NUAK1 and clinicopathologic factors and patient outcomes including progression-free s ...[more]
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