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Potent triazine-based dehydrocondensing reagents substituted by an amido group.

ABSTRACT: This study describes the synthesis of triazine-based dehydrocondensing reagents substituted by amido substituents and demonstrates their efficiency for dehydrocondensing reactions in MeOH and THF. N-Phenylbenzamido-substituted chlorotriazine is readily converted to a stable, non-hygroscopic triazinylammonium-based dehydrocondensing reagent that is superior to 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM) in terms of its reactivity in dehydrocondensing reactions.

SUBMITTER: Kunishima M

PROVIDER: S-EPMC5082469 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Potent triazine-based dehydrocondensing reagents substituted by an amido group.

Kunishima Munetaka M Kato Daiki D Kimura Nobu N Kitamura Masanori M Yamada Kohei K Hioki Kazuhito K

Beilstein journal of organic chemistry 20160824

This study describes the synthesis of triazine-based dehydrocondensing reagents substituted by amido substituents and demonstrates their efficiency for dehydrocondensing reactions in MeOH and THF. <i>N</i>-Phenylbenzamido-substituted chlorotriazine is readily converted to a stable, non-hygroscopic triazinylammonium-based dehydrocondensing reagent that is superior to 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM) in terms of its reactivity in dehydrocondensing reactio ...[more]

PMID: 27829896

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