Obesity associated with increased brain age from midlife.
Ontology highlight
ABSTRACT:
SUBMITTER: Ronan L
PROVIDER: S-EPMC5082766 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
Obesity associated with increased brain age from midlife.
Ronan Lisa L Alexander-Bloch Aaron F AF Wagstyl Konrad K Farooqi Sadaf S Brayne Carol C Tyler Lorraine K LK Fletcher Paul C PC
Neurobiology of aging 20160727
Common mechanisms in aging and obesity are hypothesized to increase susceptibility to neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We therefore performed a cross-sectional analysis of magnetic resonance image-based brain structure on a population-based cohort of healthy adults. Study participants were originally part of the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) and included 527 individuals aged 20-87 years. Cortical reconstruction techniq ...[more]
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