Ontology highlight
ABSTRACT:
SUBMITTER: Naylor RW
PROVIDER: S-EPMC5085044 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Naylor Richard W RW McGhee Charles N J CN Cowan Chad A CA Davidson Alan J AJ Holm Teresa M TM Sherwin Trevor T
PloS one 20161028 10
Corneal diseases such as keratoconus represent a relatively common disorder in the human population. However, treatment is restricted to corneal transplantation, which only occurs in the most advanced cases. Cell based therapies may offer an alternative approach given that the eye is amenable to such treatments and corneal diseases like keratoconus have been associated specifically with the death of corneal keratocytes. The ability to generate corneal keratocytes in vitro may enable a cell-based ...[more]