Ontology highlight
ABSTRACT:
SUBMITTER: Pan CW
PROVIDER: S-EPMC5085214 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Pan Chun-Wu CW Liu Hailong H Zhao Yu Y Qian Chenchen C Wang Liguo L Qi Jun J
Oncotarget 20160601 23
Bladder cancer is one of the most common malignancies of the urinary system, and the 5-year survival rate remains low. A comprehensive understanding of the carcinogenesis and progression of bladder cancer is urgently needed to advance treatment. c-Jun N-terminal kinase-2 (JNK2) exhibits both tumor promoter and tumor suppressor actions, depending on tumor type. Here, we analyzed the JNK2 function in bladder cancer. Using gene expression microarrays, we demonstrated that JNK2 mRNA is downregulated ...[more]