Ontology highlight
ABSTRACT:
SUBMITTER: Lin X
PROVIDER: S-EPMC5087313 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Lin Xuling X DeAngelis Lisa M LM
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20150817 30
Brain metastases (BMs) occur in 10% to 20% of adult patients with cancer, and with increased surveillance and improved systemic control, the incidence is likely to grow. Despite multimodal treatment, prognosis remains poor. Current evidence supports use of whole-brain radiation therapy when patients present with multiple BMs. However, its associated cognitive impairment is a major deterrent in patients likely to live longer than 6 months. In patients with oligometastases (one to three metastases ...[more]