Ontology highlight
ABSTRACT:
SUBMITTER: Zhao S
PROVIDER: S-EPMC5095349 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Nature communications 20161027
It is difficult to achieve minimally invasive injectable cell delivery while maintaining high cell retention and animal survival for in vivo stem cell therapy of myocardial infarction. Here we show that pluripotent stem cell aggregates pre-differentiated into the early cardiac lineage and encapsulated in a biocompatible and biodegradable micromatrix, are suitable for injectable delivery. This method significantly improves the survival of the injected cells by more than six-fold compared with the ...[more]