Ontology highlight
ABSTRACT:
SUBMITTER: Li H
PROVIDER: S-EPMC5097023 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Li Hongda H Saucedo-Cuevas Laura L Regla-Nava Jose A JA Chai Guoliang G Sheets Nicholas N Tang William W Terskikh Alexey V AV Shresta Sujan S Gleeson Joseph G JG
Cell stem cell 20160818 5
Zika virus (ZIKV)-related neuropathology is an important global health concern. Several studies have shown that ZIKV can infect neural stem cells in the developing brain, but infection in the adult brain has not been examined. Two areas in the adult mouse brain contain neural stem cells: the subventricular zone of the anterior forebrain and the subgranular zone of the hippocampus. Here, using 6-week-old mice triply deficient in interferon regulatory factor (IRF) as a model, we show that blood-bo ...[more]