Ontology highlight
ABSTRACT:
SUBMITTER: Ko D
PROVIDER: S-EPMC5097881 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Ko Darae D Riles Eric M EM Marcos Ernaldo G EG Magnani Jared W JW Lubitz Steven A SA Lin Honghuang H Long Michelle T MT Schnabel Renate B RB McManus David D DD Ellinor Patrick T PT Ramachandran S Vasan SV Wang Thomas J TJ Gerszten Robert E RE Benjamin Emelia J EJ Yin Xiaoyan X Rienstra Michiel M
The American journal of cardiology 20160824 10
Previous studies have shown several metabolic biomarkers to be associated with prevalent and incident atrial fibrillation (AF), but the results have not been replicated. We investigated metabolite profiles of 2,458 European ancestry participants from the Framingham Heart Study without AF at the index examination and followed them for 10 years for new-onset AF. Amino acids, organic acids, lipids, and other plasma metabolites were profiled by liquid chromatography-tandem mass spectrometry using fa ...[more]