Ontology highlight
ABSTRACT:
SUBMITTER: Yu H
PROVIDER: S-EPMC5101276 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Yu Haiyang H Chakravorty Samya S Song Weihua W Ferenczi Michael A MA
European biophysics journal : EBJ 20160415 8
Phosphorylation of the regulatory light chain (RLC) of myosin modulates cellular functions such as muscle contraction, mitosis, and cytokinesis. Phosphorylation defects are implicated in a number of diseases. Here we focus on striated muscle where changes in RLC phosphorylation relate to diseases such as hypertrophic cardiomyopathy and muscular dystrophy, or age-related changes. RLC phosphorylation in smooth muscle and non-muscle cells are covered briefly where relevant. There is much scientific ...[more]