Ontology highlight
ABSTRACT:
SUBMITTER: Grebely J
PROVIDER: S-EPMC5106608 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Grebely Jason J Dore Gregory J GJ Zeuzem Stefan S Aspinall Richard J RJ Fox Raymond R Han Lingling L McNally John J Osinusi Anu A Brainard Diana M DM Subramanian G Mani GM Natha Macky M Foster Graham R GR Mangia Alessandra A Sulkowski Mark M Feld Jordan J JJ
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20160823 11
In this analysis of the ASTRAL trials (non-opioid substitution therapy [OST], n = 984; OST, n = 51) evaluating the once-daily, pan-genotypic regimen of sofosbuvir/velpatasvir for hepatitis C virus infection, OST did not impact completion, adherence, sustained virologic response (SVR12), or safety. SVR12 was 96% (95% confidence interval, 87%, >99%) in those receiving OST. ...[more]