Ontology highlight
ABSTRACT:
SUBMITTER: Green R
PROVIDER: S-EPMC5107684 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Green Richard R Wilkins Courtney C Thomas Sunil S Sekine Aimee A Ireton Renee C RC Ferris Martin T MT Hendrick Duncan M DM Voss Kathleen K Pardo-Manuel de Villena Fernando F Baric Ralph S RS Heise Mark T MT Gale Michael M
Genomics data 20161014
West Nile Virus (WNV) is a mosquito-transmitted virus from the Flaviviridae family that causes fever in 1 in 5 infected people. WNV can also become neuro-invasive and cross the blood-brain barrier leading to severe neurological symptoms in a subset of WNV infected individuals [1]. WNV neuro-invasion is believed to be influenced by a number of factors including host genetics. In order to explore these effects and recapitulate the complex immune genetic differences among individuals, we studied ge ...[more]