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Nanofabricated Neural Probes for Dense 3-D Recordings of Brain Activity.


ABSTRACT: Computations in brain circuits involve the coordinated activation of large populations of neurons distributed across brain areas. However, monitoring neuronal activity in the brain of intact animals with high temporal and spatial resolution has remained a technological challenge. Here we address this challenge by developing dense, three-dimensional (3-D) electrode arrays for electrophysiology. The 3-D arrays constitute the front-end of a modular and configurable system architecture that enables monitoring neuronal activity with unprecedented scale and resolution.

SUBMITTER: Rios G 

PROVIDER: S-EPMC5108031 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature

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Nanofabricated Neural Probes for Dense 3-D Recordings of Brain Activity.

Rios Gustavo G   Lubenov Evgueniy V EV   Chi Derrick D   Roukes Michael L ML   Siapas Athanassios G AG  

Nano letters 20161021 11


Computations in brain circuits involve the coordinated activation of large populations of neurons distributed across brain areas. However, monitoring neuronal activity in the brain of intact animals with high temporal and spatial resolution has remained a technological challenge. Here we address this challenge by developing dense, three-dimensional (3-D) electrode arrays for electrophysiology. The 3-D arrays constitute the front-end of a modular and configurable system architecture that enables  ...[more]

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