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Discrimination and Integration of Stress Signals by Pathogenic Bacteria.

ABSTRACT: For pathogenic bacteria, the ability to sense and respond to environmental stresses encountered within the host is critically important, allowing them to adapt to changing conditions and express virulence genes appropriately. This review considers the diverse molecular mechanisms by which stress conditions are sensed by bacteria, how related signals are discriminated, and how stress responses are integrated, highlighting recent studies in selected bacterial pathogens of clinical relevance.

SUBMITTER: Fang FC

PROVIDER: S-EPMC5111874 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature

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Discrimination and Integration of Stress Signals by Pathogenic Bacteria.

Fang Ferric C FC Frawley Elaine R ER Tapscott Timothy T Vázquez-Torres Andrés A

Cell host & microbe 20160801 2

For pathogenic bacteria, the ability to sense and respond to environmental stresses encountered within the host is critically important, allowing them to adapt to changing conditions and express virulence genes appropriately. This review considers the diverse molecular mechanisms by which stress conditions are sensed by bacteria, how related signals are discriminated, and how stress responses are integrated, highlighting recent studies in selected bacterial pathogens of clinical relevance. ...[more]

PMID: 27512902

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