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Cascade bicyclization of triethylammonium thiolates with hydrazines: efficient access to pyrazolo[3,4-c]quinolines.

ABSTRACT: A new bicyclization strategy has been established, allowing a flexible and practical approach to 33 examples of pyrazolo[3,4-c]quinolines from low-cost and readily accessible triethylammonium thiolates with hydrazines. Notably, the features of this work include broad functional group compatibility, mild reaction conditions and good reaction yields.

SUBMITTER: Fan W

PROVIDER: S-EPMC5113139 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature

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Cascade bicyclization of triethylammonium thiolates with hydrazines: efficient access to pyrazolo[3,4-c]quinolines.

Fan Wei W Li Yan-Rong YR Jiang Bo B Li Guigen G

Organic & biomolecular chemistry 20160901 38

A new bicyclization strategy has been established, allowing a flexible and practical approach to 33 examples of pyrazolo[3,4-c]quinolines from low-cost and readily accessible triethylammonium thiolates with hydrazines. Notably, the features of this work include broad functional group compatibility, mild reaction conditions and good reaction yields. ...[more]

PMID: 27722433

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