Ontology highlight
ABSTRACT:
SUBMITTER: Kapoor M
PROVIDER: S-EPMC5113255 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Scientific reports 20161117
Alcohols and epoxides were generated by the addition of organohalides to carbonyl compounds in the presence of sodium metal impregnated with silica gel (Na@SiO<sub>2</sub>) in THF at 25 °C through a radical pathway. Under the same conditions, Schiff bases were also successfully converted to the corresponding amines. Furthermore, the reaction of aldehydes with α-haloesters or 4-(chloromethyl)-coumarin with the aid of Na@SiO<sub>2</sub> generated trans epoxides. An unprecedented mechanism is propo ...[more]